Speaking during the annual lecture to mark the birthday of Nelson Mandela, Antonio Guterres accused world powers of ignoring inequality in global institutions.
Guterres said that current national responses to the coronavirus pandemic won't address the scale and complexity of the crisis.
The United States told the United Nations that the killing of Iranian commander Qassem Soleimani last week was self-defence.
Turkey pounded US-allied Kurdish militia in Syria for a second day on Thursday, forcing tens of thousands of people to flee and killing dozens.
North Korea blamed the US for a failure to restart stalled talks, more than a year after President Donald Trump's first meeting with North Korean leader Kim Jong Un.
Swedish teenage climate activist Greta Thunberg shot back at U. S. President Donald Trump's attempt to mock her on Twitter.
The UN Security Council is considering lifting sanctions on Eritrea next week after a rapprochement with Ethiopia.
The UN welcomed warming ties between Eritrea and Ethiopia, but diplomats said it stopped short of pledging that it could review sanctions on Eritrea.
More than 120 countries voted in favour of a General Assembly resolution calling for the US to withdraw its decision to recognize Jerusalem as Israel's capital.
The UN Security Council will vote on a draft resolution calling for the withdrawal of US President Donald Trump's decision to recognize Jerusalem as the capital of Israel
DRC must hold a long-delayed election to replace President Joseph Kabila by the end of next year or the vote will lose international support.
The UN Security Council unanimously stepped up sanctions against North Korea over the country's sixth and most powerful nuclear test.
The UN has appointed an investigator to help protect gay and transgender people worldwide - and African states didn't like that.
The number of besieged Syrians has more than doubled over the past year to nearly one million, the UN aid chief told the Security Council.
The election of Donald Trump as the next US president was met with disbelief and despondency among some United Nations officials.
South Africa is reportedly planning to leave the International Criminal Court.
Displaced civilians and religious leaders in war-torn South Sudan appealed to the UN Security Council to urgently deploy extra foreign troops.
The United Nations Security Council has authorised the deployment of up to 228 UN police to Burundi to monitor security.
The UN is ready to work with IGAD to refine the East African bloc’s proposal for an intervention force in South Sudan.
The UN Security Council expressed serious concern over the failure of South Sudanese rebel leader Riek Machar to return to Juba.
Tanzanian peacekeepers in the DRC reportedly abused and exploited five women and six girls, leaving them all pregnant, the UN said.
The UN said it had received new allegations of sexual abuse and exploitation against UN peacekeepers from Morocco and Burundi in Central African Republic.
UN chief Ban Ki-moon regrets a “misunderstanding” over his use of the word “occupation” to describe Morocco's annexation of Western Sahara.
UN sanctions monitors say Islamic State has greatly expanded its control over territory in Libya, and claim to be the country’s key defence against foreign forces.
Congolese troops killed two UN peacekeepers after civilians accused the Tanzanian UN troops of providing supplies to Islamist Ugandan rebels.