World No 2 Aryna Sabalenka was on a streak of 15 victories in a row, claiming titles in Cincinnati and then the US Open for the first time before the defeat at the China Open.
Chile's Alejandro Tabilo stunned the tennis world by dismantling 24-time Grand Slam champion Djokovic in straight sets on Sunday.
World No 1 Novak Djokovic was left crouched on the ground in agony as the bottle hit him on the back of the head at the Rome Open.
The American third seed Coco Gauff was plagued by multiple double-faults in a fourth-round defeat last week to compatriot Madison Keys in Madrid.
Tunisian tennis star Ons Jabeur has called out organisers of European tournaments for failing to ‘respect’ women players by giving preferential treatment to men.
Defending Madrid Open champions Carlos Alcaraz and Aryna Sabalenka both triumphed in their opening clashes in the Spanish capital on Friday to reach the third round.
Naomi Osaka and Iga Swiatek enjoyed winning returns to the Billie Jean King Cup to move Japan and Poland closer to the finals.
World number one Iga Swiatek was knocked out of the Miami Open after third-ranked Coco Gauff was also defeated on Monday.
World number two Aryna Sabalenka returned to the court for the first time since the death of her former boyfriend earlier this week and kept her emotions in check.